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Table 3 Serum concentrations of sex hormones and SHBG before the dietary study perioda Weight changes over the study period were not great in both groups. The means of 0—8 week change were 1. The means of 2—12 week values for estrone were We repeated the analysis after excluding the three subjects with nondetectable estrone levels.
The results were not altered substantially. Discussion We observed a significant difference between the soymilk-supplemented group and the control group in terms of changes in serum estrone concentrations over the study period 12 weeks.
Soymilk supplementation may affect circulating estrone concentrations. The intervention was conducted for 8 weeks. The results from the analysis for the week period should include a reflection of a delayed effect of the intervention. However, we cannot exclude the possibility that the participants in the soymilk-supplemented group made some change during the 4 weeks after the intervention that affected the results.
It is difficult to interpret the increase in serum estrone concentrations over time in the control group, although this increase was not statistically significant. Because a positive association between alcohol intake and serum estrogen concentration has been reported 2526one might argue that a nonsignificant increase in alcohol intake in the control group may be responsible for the difference between the two groups in the changes in serum estrone.
We had asked the subjects to maintain their usual lifestyle, but we could not control or monitor their activities during the study period. However, considering that nutrient intakes were similar before and after the dietary study period in the control group, it is unlikely that the subjects changed their lifestyle substantially as a result of assignment to the control group.
Although it is unclear which factor caused the moderate increase in serum estrone concentration observed in the control group, it is likely that exposure to this factor occurred in both groups. It is also possible that the decrease in serum estrone over time in the soymilk-supplemented group may be attributable to a change in diet or lifestyle variables other than soymilk intake.
However, the main dietary change was the intake of nutrients rich in soymilk in the soymilk-supplemented group. In addition, several known properties of soy isoflavones suggest the mechanism by which soy intake can modify serum estrogen concentrations.
Isoflavones also inhibit cytochrome P isozymes responsible for estrogen hydroxylations Estrogenicity of soy may exert an effect on the hypothalamic-pituitary-gonadal axis and ultimately down-regulate the estrogen synthesis.
The inhibition effect of isoflavones on binding of estrogen to SHBG may also accelerate steroid metabolism The reason for the lack of change in estradiol concentration is not clear. The rate of peripheral formation derived from the aromatization of androgen is greater in estrone than in estradiol 31which may be related in part to the differential effects of the soymilk consumption.
It is not clear whether decreased estrone concentrations lead to a reduction in the risk of prostate cancer. Estrogens have been suggested to be involved in the development of prostate cancer.
However, epidemiological studies on serum estrogen concentrations and the risk of prostate cancer have yielded varying results.
Higher estrogen concentrations in cases than those in controls have been reported in some studies 3233 but not in others 1516 Testosterone has been strongly implicated in the etiology of prostate cancer In the present study, we did not find any differences in changes of total and free-testosterone concentrations between the two groups.
To our knowledge, there has been no other dietary intervention study that has investigated the effect of soy consumption on serum androgens in men. Furthermore, our study is the first based on a randomized design.
|Research papers for science||References Soy Tofu, tempeh, edamame, soymilk and miso are a few of the soy foods people around the world enjoy every day.|
We assessed previously the effect of soy intake on serum estrogens in premenopausal women in a cross-sectional study 36 and an intervention study Soy milk research papers Bram 26/07/ Best research, and lux research house eating allergies successfully elevated the health and milk and soy supplements as than skim milk by.
1 cup soy milk; 1/2 cup cooked soy beans; Related Links: The Cancer Research. Soy foods contain several key nutrients and phytochemicals studied for their cancer prevention properties.
Many soy foods also contain dietary fiber, which links to lower risk of colorectal cancer. Soy foods contain isoflavones, which are phytoestrogens that in. Research continues to expand the positive role milk and dairy foods play in an individual's health.
Evidence goes well beyond building strong bones (read more about milk and bone health) to include its effects on blood pressure, heart disease and diabetes prevention and weight management efforts, among other positive effects.
½ cup soy milk = 15 mg; ½ cup edamame = 12 mg; Total = 80 mg of PEs; No more rats: Humans and phytoestrogens. Taking it to human studies, data on patients with prostate cancer showed that the intake of 80 mg/day of PEs did not significantly alter testosterone levels.
Milk research in present days gained high importance because of its healths effects in both the ways. Research include improving quality, nutrients, Low fat content, Dairy storage and shelf life etc.. Related Journals to Milk Research.
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Benefits of Soy. Length: words ( double-spaced pages) have found myself learning and experiementing with making different batchs of different recipes of different flavors of soy milk. It all started because I had been thinking about getting a.